Molecular Biology: Protein Structure and Functions - Stepanov V.M. 2005
Acid-Base Properties of Amino Acids
Chemical Reactions of α-Amino Acids
Methods for the Synthesis of α-Amino Acids
Chemical properties of peptides
Chemical synthesis of peptides
Protein Isolation
Specifics of Protein Isolation
Characteristic properties of proteins underlying their separation
Separation of proteins by molecular weight. Gel chromatography (gel filtration)
Ion-Exchange Chromatography of Proteins
Hydrophobic Interaction Chromatography of Proteins
Affinity (Biospecific) Protein Chromatography
Prospects for Using Protein Engineering in Protein Isolation
Primary protein structure
Primary structure as a level of protein organization
Primary Structure of Proteins
Proof of Protein Individuality. Protein Microheterogeneity
Primary Protein Structure
Determination of the Amino Acid Composition of a Protein
Primary protein structure
Methods for determining primary structure
Determination of the primary structure of peptides
Secondary Structure
Structural features of the peptide bond
Steric constraints and secondary structure of the peptide chain
The Role of Hydrogen Bonds in the Formation of Secondary Structure
On the Stability of Secondary Structure
On the Relationship Between Primary and Secondary Structures
Secondary structure
Optical methods for studying secondary structure
Tertiary Protein Structure
Stability of the Three-Dimensional Protein Structure
Tertiary protein structure
Tertiary Protein Structure
The role of disulfide bonds in stabilizing the tertiary structure of certain proteins
Shape, compactness, and dynamics of the protein molecule
Tertiary protein structure
Tertiary Protein Structure
Formation of the tertiary protein structure from secondary structure elements
Polypeptide chain topology in proteins and classification of spatial structures
Structural Features of Membrane Proteins
Tertiary protein structure
Tertiary Protein Structure
On the Relationship Between Primary and Spatial Protein Structures
Stoichiometry and geometry of quaternary structure
Quaternary Protein Structure
Subunit interactions stabilizing the quaternary structure
Structural organization of subunit interfaces
Methods for Investigating Quaternary Structure
Functional Significance of Quaternary Protein Structure
Chemical protein modification
Features of the chemical modification method
Chemical modification of proteins
Standard reactions for the chemical modification of protein functional groups
Applications of the chemical modification method
General Concepts of Enzymatic Catalysis
Basic Principles of Enzyme Catalysis Kinetics
Catalytic antibodies ("abzymes")
Post-translational Protein Modification
Intramolecular Rearrangements in Proteins
Post-translational protein modification
Iodination of tyrosine residues
Post-translational Protein Modification
Formation of γ-carboxyglutamic acid residues
Post-translational protein modification
Protein glycosylation. Glycoproteins
Post-translational Protein Modification
Protein Phosphorylation. Phosphoproteins
Post-translational protein modification
Processing of the amino-terminal region of a protein
G proteins
Stimulatory Gs protein and inhibitory Gi protein of the adenylate cyclase system
Immunoglobulins
Molecular organization of immunoglobulin G
The Diversity of Immunoglobulins
Fibrous proteins
Fibrillar proteins
Fibrous proteins