Genetics - A. V. Sivolob 2008

Formal Genetics: Patterns of Trait Inheritance
Crossing-over
Gene Conversion

The phenomenon of Gene conversion is closely linked to The process of Homologous Recombination, regardless of whether a reciprocal exchange of segments between homologous Chromosomes has taken place (see Section 1). As shown in Fig. 3.14, resulting from a conversion event where allele B is transformed into b or vice versa, a Bb heterozygote can produce Two Types of Gametes in a 3 : 1 ratio. In genetic analysis via crosses, such gametes may formally be regarded as double crossovers (cf. Fig. 3.12) characterized by negative Interference—yielding a high frequency of "double crossovers" in the absence of flanking crossover products between the A/a and C/c loci.

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Fig. 3.14. Tetrad in prophase I of Meiosis and two Variants of the gamete set produced in the event of B/b gene conversion between two homologous chromatids

It should be noted that gene conversion provides diploid organisms with a mechanism to restore Genetic information that has been damaged by a mutation in one of the two homologous chromosomes (see also Section 5).



Last update: 11/08/2026

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