Obstetrics and Gynecology - A.M. Hromova 2000

Background and precancerous conditions of the female reproductive organs

The basis of Background and precancerous conditions is the proliferation of Cells in the basal layer of the stratified squamous epithelium and the metaplasia of the columnar epithelium, followed by its atypia.

The Development of these pathological states can be triggered by chronic inflammatory processes, particularly those caused by Herpes simplex virus type 2 and human papillomavirus, as well as infectious factors such as pyospermia in a partner, Gonorrhea, Trichomoniasis, and chlamydia.

Risk factors include early onset of sexual activity and frequent change of sexual partners. Pathological processes of the cervix are frequently associated with uterine fibroids, Dysfunctional Uterine Bleeding, and dyshormonal Breast Diseases. This confirms The Link Between functional disorders in the hypothalamo-ovarian system and the development of diseases in target Organs (the Uterus, Mammary Glands, and cervix).

The susceptibility of various organs depends on the state of their receptor apparatus, the impairment of which leads to pathology. Pathological changes occurring in the cervix vary in Etiology, Morphology, and their significance in the development of Cancer; therefore, they can be divided into three subgroups: background changes, precancer, and cancer. Epithelial malignant formations of the cervix are preceded by precancerous epithelial changes that can develop either on an unchanged cervix or within the area of background processes. For practical purposes, the Classification by I.O. Yakovleva and B.G. Kukuta (1977) is utilized.

Class="center">Classification of background diseases, precancerous conditions, and Cervical cancer