Pathological Anatomy. Atlas of Gross Specimens - Part 2. Pathology of Individual Organs and Systems - A. M. Romanyuk 2016
Pathology of the Urinary System
Nephrolithiasis
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The specimen shows structural Impairment of the renal parenchyma. This is caused by the presence of numerous renal calculi and impaired urine outflow, which leads to The Development of atrophy and sclerotic Changes in the Kidney tissue. The key pathogenetic mechanisms of urolithiasis include increased salt concentration in the urine, shifts in urinary pH and colloidal balance, and The formation of a colloidal (protein) matrix for stone development.
Last update: 10/08/2026
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