GENERAL MICROBIOLOGY - T.P. Pyrog - 2004

11. MAIN MECHANISMS OF METABOLISM AND ENERGY CONVERSION IN MICROORGANISMS

11.6. RESPIRATORY CHAIN AND PHOSPHORYLATION (ATP SYNTHESIS) DURING ELECTRON TRANSFER

11.6.9. Inhibitors of the respiratory chain

Let us consider the Inhibitors of the Respiratory Chain in which oxygen serves as the terminal electron acceptor. Amital and rotenone inhibit The activity of NADH dehydrogenase. Antimycin A blocks electron transfer between Cytochromes b and c. Cyanide and carbon monoxide (CO) inhibit only cytochrome c oxidase, but not cytochrome c. The specific action of these toxic agents, along with Changes in the characteristic absorption spectra of respiratory chain components, served as indicators used to map and study this chain.

Last update: 12/08/2026

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