Obstetrics and Gynecology - A.M. Hromova 2000

Background and precancerous conditions of the female reproductive organs
Endometrial hyperplastic processes
Clinical presentation

The Development of disease symptoms often depends on the patient's age. A characteristic symptom is menstrual irregularities. Women with a preserved Menstrual cycle experience bleeding that is more commonly cyclic and less frequently acyclic. Sometimes, bleeding occurs in the middle of the menstrual cycle. The substrate of this bleeding is typically an area of hyperplastic endometrium featuring pronounced degenerative changes and foci of necrosis, along with markedly dilated Blood Vessels and thrombosis.

Hyperplastic processes occur most frequently in women aged 40–50. These patients are typically characterized by a relatively late onset of postmenopause. Many women exhibit disturbances in lipid and Carbohydrate METABOLISM, impaired protein-synthesizing Liver function, and altered functional activity of The Thyroid Gland.

During a gynecological examination in the Cytology/cytology/16.html">Early stages of the disease, pathological Changes in the reproductive Organs may not be detected. As the condition progresses, a slight enlargement of the Uterus and a firmer consistency are observed. Subsequently, these manifestations are accompanied by bilateral cystic enlargement of the Ovaries, and occasionally hormone-dependent ovarian tumors develop, particularly in elderly women.