Obstetrics and Gynecology - A.M. Gromova 2000

Diseases of Newborns
Toxic and Septic Diseases of Newborns

The anatomical and PHYSIOLOGICAL CHARACTERISTICS OF newborns, the immaturity of the barrier Functions of the Skin and mucous membranes, and reduced immunological reactivity determine their high susceptibility to purulent-septic infections.

Infection can occur prenatally from an ill mother (rheumatism, Pyelonephritis), intranatally (endometritis, Premature Rupture of amniotic membranes, colpitis), and postnatally through failure to comply with asepsis and antisepsis rules (diapers, instruments, endotracheal tubes, etc., as well as from germ carriers).

The causative factor of most diseases is gram-positive microorganisms (staphylococci and streptococci), although recently gram-negative microbes (Klebsiella, Escherichia coli, Pseudomonas aeruginosa, Pseudomonas) have increasingly become the causative agents of diseases.



Last update: 08/08/2026

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