PRACTICAL COURSE IN HISTOLOGY, CYTOLOGY AND EMBRYOLOGY - 2016

Chapter 4. TISSUES

Slide 51. Development of bone in place of connective tissue.

Staining: hematoxylin and eosin.

Magnification: x400.

Under low magnification, we observe islands (trabeculae) of coarse-fibered Bone tissue (1), which are homogeneously stained pink. The islands are surrounded On the surface by polygonal Cells with large violet nuclei—osteoblasts (2). The islands are located among mesenchymal cells interconnected by processes (3). Inside the islands, there are bone lacunae containing osteocytes (4). Along the edge of the bone trabecula, depressions can occasionally be distinguished, housing an osteoclast (5)—a large Cell with two to three nuclei and acidophilic Cytoplasm.

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Slide 51. Development of bone in place of Connective Tissue.

Last update: 07/08/2026

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