BIOCHEMISTRY - L. Stryer - 1984

VOLUME 2

PART III. BIOSYNTHESIS OF MACROMOLECULAR PRECURSORS

CHAPTER 20. BIOSYNTHESIS OF MEMBRANE LIPIDS AND STEROID HORMONES

QUESTIONS AND PROBLEMS

1. Write a balanced equation for the synthesis of triacylglycerol from glycerol and Fatty acids.

2. Write a balanced equation for the de novo synthesis of phosphatidylserine from Serine, glycerol, and fatty acids.

3. Indicate the activated precursor form in each of the following biosynthetic reactions:

a) phosphatidylserine from serine;

b) phosphatidylethanolamine from ethanolamine;

c) ceramide from sphingosine;

d) sphingomyelin from ceramide;

e) cerebroside from ceramide;

f) ganglioside Gм1 from ganglioside GМ2;

g) farnesyl pyrophosphate from geranyl pyrophosphate.

4. How is the isotopic label distributed in a Cholesterol molecule synthesized from the following precursors?

a) mevalonate labeled with 14C at the carboxyl carbon atom?

b) malonyl-CoA labeled with 14C at the carboxyl carbon atom?



Last update: 06/08/2026

Editorial and Educational Adaptation: This material has been compiled based on the primary/original source text. The project team performed an editorial review, corrected technical inaccuracies, structured sections, and adapted the content for an educational format.

What was processed:

  • elimination of formatting defects (OCR errors, structural breaks, corrupted characters);
  • editorial organization of content;
  • standardization of terminology in accordance with academic sources;
  • verification of factual statements against the original source text.

All mentions of the author, publication year, and origin of the primary text have been preserved in accordance with the source.