Human Biochemistry, Volume 2 - Murray R. 1993

Specialized Topics
Cancer, Oncogenes, Growth Factors
Oncogenic Viruses – Transformation

Cultured Cells infected with certain Oncogenic Viruses can undergo malignant transformation. The most significant morphological and biochemical changes associated with this transformation are listed in Table 57.5. These changes affect Cell shape, motility, growth, and adhesion to the culture substrate, as well as A number of biochemical processes. We are referring to both primary processes that cause The conversion of a normal cell into a tumor cell, and secondary processes resulting from this conversion. Of great importance in carcinogenesis research is the concept that cell transformation is associated with the acquisition of "special" properties. However, cellular changes known collectively as "transformation" still do not make transformed cells identical to tumor cells in vivo.



Last update: 06/08/2026

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