Biochemistry, Vol. 3 - A. Lehninger 1985

Selected Aspects of Human Biochemistry
Human Nutrition
Riboflavin deficiency is a phenomenon as common as ascorbic acid deficiency

Mild riboflavin deficiency (Fig. 26-12) is relatively common in many countries, including the United States. It has not attracted widespread attention because it is almost never life-threatening. Riboflavin deficiency occurs most frequently in pregnant women, growing children, and individuals under physical stress. Typical manifestations include irritation and cracking of the Lips and the corners of the Mouth, as well as facial dermatitis. Anemia is sometimes observed as well. Riboflavin deficiency frequently occurs concurrently with other vitamin deficiencies, such as in pellagra.

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Fig. 26-12. Structure, function, and recommended daily allowance of riboflavin.

The best dietary sources of riboflavin are milk, Liver, eggs, meat, and yellow vegetables. Because bread and cereals contain very little riboflavin, it is frequently added to these products.



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