Biological Chemistry - Berezov, T. T., Korovkin, B. F. 1998

Vitamins
Vitamin-like Compounds
Vitamin B15

Vitamin B15 (pangamic acid) was first discovered in 1950 in bovine Liver extracts and later isolated from many plant seeds, which explains its name (from the Greek pan meaning "everywhere" and gami meaning "seed"). Neither avitaminosis nor hypervitaminosis B15 has been described in humans, although its preparations are used in medicine for certain conditions associated with Metabolic Disorders (specifically, Transmethylation reactions). Pangamic acid preparations provide a favorable therapeutic effect in Fatty liver degeneration and certain forms of oxygen deprivation.

From a chemical perspective, pangamic acid is an ester of gluconic acid and dimethylglycine.

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* The general structural formula of sulfonamide drugs can be represented as follows:

The Biological Role of vitamin B15 is not yet fully understood. There are isolated indications and hypotheses regarding its potential involvement in The Biosynthesis of Choline, Methionine, and creatine as a source of methyl groups.

Dietary sources of vitamin B15 for humans include liver, plant seeds, Yeast, and others. The daily human requirement for this vitamin has not been established.



Last update: 06/08/2026

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