Obstetrics and Gynecology - A.M. Gromova 2000

Early pregnancy toxicoses. Late gestosis
Late gestosis
Gestational proteinuria (Proteinuria gravidarum)

Gestational proteinuria is a form of Late gestosis characterized by the appearance of significant amounts of protein in the urine (greater than 0.3 g/L) after 20 weeks of gestation, in the absence of arterial Hypertension, edema, and prior renal involvement from infectious or systemic diseases. In the third trimester, a certain amount of protein excretion by the Kidneys may be observed, which is distributed unevenly throughout the day. Therefore, the presence of a trace amount of protein in a random urine sample does not yet indicate gestosis. However, it should prompt the physician to conduct a more detailed assessment of renal function, primarily by determining the protein content in a 24-hour urine collection. Proteinuria is defined as a protein loss of 300 mg per day. Depending on the severity of this symptom, three degrees of gestosis severity are distinguished:

Grade I - urinary protein loss up to 1 g/L;

Grade II - proteinuria ranging from 1 to 5 g/L;

Grade III - proteinuria exceeding 5 g/L.

The Treatment of gestational proteinuria is managed similarly to that of Preeclampsia, in accordance with the severity of the condition.



Last update: 08/08/2026

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