BIOLOGY Volume 1 - A Guide to General Biology - 2004

4. ENZYMES

4.4. Enzyme Inhibition

4.4.2. Non-competitive Reversible Inhibition

Inhibitors of this type are not structurally related to the substrate of the enzyme; in this case, the complex with the inhibitor involves another part of the enzyme molecule rather than its Active Site. This does not prevent the substrate from binding to the enzyme, but it renders catalysis impossible. As the inhibitor concentration increases, the reaction rate decreases progressively. Upon saturation with the inhibitor, the rate drops to practically zero. Unlike competitive inhibition, increasing the Substrate Concentration has no effect on the reaction rate in this case.



Last update: 06/08/2026

Editorial and Educational Adaptation: This material has been compiled based on the primary/original source text. The project team performed an editorial review, corrected technical inaccuracies, structured sections, and adapted the content for an educational format.

What was processed:

  • elimination of formatting defects (OCR errors, structural breaks, corrupted characters);
  • editorial organization of content;
  • standardization of terminology in accordance with academic sources;
  • verification of factual statements against the original source text.

All mentions of the author, publication year, and origin of the primary text have been preserved in accordance with the source.