MEDICAL BIOLOGY, ANATOMY, HUMAN PHYSIOLOGY AND PATHOLOGY - Ya.I. Fedoniuk 2010
ANATOMY, PHYSIOLOGY, PATHOLOGY
SECTION 1. ORGAN. ORGAN SYSTEM. ORGANISM
TUMORS
GENERAL CHARACTERISTICS OF TUMORS
3. TUMOR MORPHOGENESIS
Tumor morphogenesis is characterized by two stages: the stage of pre-tumor changes and the stage of tumor formation and growth.
Pre-tumor conditions include the following Background changes: dystrophy, atrophy, sclerosis, hyperplasia, metaplasia, and Dysplasia. Precancerous changes are characterized by The Development of facultative and obligate precancer, as well as the so-called latent period, which for certain tumors can last 30-40 years.
Obligate precancerous conditions encompass pathological processes and states that almost invariably lead to the development of neoplasms. Examples of such obligate precancers include congenital polyposis of the colon, xeroderma pigmentosum, neurofibromatosis, and Liver cirrhosis.
Facultative precancerous conditions include long-standing defects of the Skin, mucous membranes, and Internal Organs, regardless of their origin and formation characteristics: cervical erosion, gastric polyps, and cholelithiasis.
Last update: 08/08/2026
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