WORKSHOP IN HISTOLOGY, CYTOLOGY AND EMBRYOLOGY - 2016

Chapter 5. SPECIAL HISTOLOGY

Digestive system

Slide 110. Pig liver.

Staining: hematoxylin and picrofuchsin.

Magnification: x80.

To the naked eye, the slide has a yellowish tint. Under low magnification, Liver lobules (1) are clearly visible, separated by pink-colored Connective Tissue septa (2). At the periphery of the lobules within the connective tissue, we can observe portal triads (liver triads): interlobular artery, interlobular vein, and interlobular Bile duct. The vein (3) has a thin wall, while the artery (4) has a thicker wall with numerous smooth myocytes, whose nuclei are elongated along the vessel perimeter. The duct (5) differs from the vessels by the presence of cuboidal epithelium with large, round, purple-colored nuclei. In the center of the lobule, we can see the central vein (6), from which sinusoidal capillaries (sinusoids) (7) radiate outward. Their endothelial Cells feature elongated nuclei. Between the sinusoids lie hepatocyte plates (cords) (8) with large, pale nuclei. The structural details of the liver lobule are schematically illustrated separately at high magnification.

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Slide 110. Pig liver.



Last update: 07/08/2026

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