GENERAL MICROBIOLOGY - T.P. Pyrog - 2004

20. METABOLIC REGULATION

20.3. MECHANISMS OF ENZYME SYNTHESIS (INDUCTION AND REPRESSION)

The Introduction/15.html">Regulation of enzyme synthesis occurs at the METABOLISM/31.html">Transcription level. This type of regulation requires specific signals to be delivered to the DNA from other PARTS OF THE Cell. Signaling molecules (effector molecules) are low-molecular-weight compounds (such as sugars and their derivatives, Amino Acids, and NUCLEOTIDES). Since these effectors cannot interact directly with DNA, a specific regulatory protein serves as an intermediary for each of them. A regulatory protein that binds to DNA in the absence of an effector (inducer) is called a repressor. A regulatory protein that binds to DNA in the presence of an effector (corepressor) is called an aporepressor.



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