MEDICAL BIOLOGY, HUMAN ANATOMY, PHYSIOLOGY AND PATHOLOGY - Ya.I.Fedoniuk 2010
ANATOMY, PHYSIOLOGY, PATHOLOGY
SECTION 4. BLOOD SYSTEM
PATHOLOGY OF THE BLOOD SYSTEM
QUANTITATIVE BLOOD CHANGES
3. THROMBOCYTOPENIAS AND THROMBOCYTOPATHIES
Thrombocytopenias represent a group of disorders characterized by a decreased platelet count in the Blood. These conditions can be caused by increased platelet destruction or consumption, as well as impaired platelet production. Both acquired and hereditary thrombocytopenias are distinguished.
Acquired thrombocytopenias may result from autoimmune aggression, mechanical trauma associated with Splenomegaly, suppression of Bone Marrow hematopoiesis due to radiation or chemical injury, or increased platelet demand (such as thrombosis in DIC syndrome), among other factors.
Hereditary thrombocytopenias are rooted in alterations of various platelet properties, known as thrombocytopathies.
Thrombocytopathies comprise a group of diseases and syndromes characterized by qualitative platelet deficiency or dysfunction.
The morphological manifestation of thrombocytopenias and thrombocytopathies is hemorrhagic diathesis—a predisposition to recurrent bleeding episodes that occur spontaneously or following minor trauma.
Last update: 08/08/2026
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